• 5 Posts
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Joined 1 year ago
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Cake day: June 14th, 2023

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  • In many cases,in the US, the rack rate for a full course of a serious cancer is easily the $500k I suggested and frequently more than double that. My treatment for a suspected single point melanoma was close to $75,000 and it was a single outpatient procedure with a pre- and post-op office follow up. No chemo, no stage designation, nothing - zero cancer found at the site of the questionable biopsy site.

    It’s true the Luxturna is an odd case (though the OP article is talking about customized treatment so it is appropriate here). It’s not the disease or cure but the justification of how they determined the cost of their treatment. Not based on the research cost or market, not based on the production or application of the treatment, but on the value of your eyesight they would be preserving.






  • No it will be more expensive. The pricing would be based on how much it currently costs, priced competitively (95% of, say, $500,000) and then they’d add $500,000 to account for the fact that you would recover more of your life and avoid suffering, so $950k total. Of course they may simply price is based on the value of your life. Say the average value of a human is $1.5M in a typical wrongful death suit; they might price it at $1.25M - a bargain!.

    Before you laugh at my logic, I’ll point out that Luxturna priced their retinal degeneration drug based on how much value courts placed on lost eyesight. They found that to be around the million-dollar range. The price of treatment was then set at $850,000, because that’s clearly providing value over the monetary equivalent of loss of eyesight (Jeffrey Marrazzo, CEO, was quoted in an interview that this was the basis). Of course, there’s an evilly fun MBA discussion to be had, as well, as your pricing could also be how much it’s worth to a parent not to have to watch their children slowly and unavoidably go blind as they become teenagers. Other drugs are often based on the cost avoidance or value of human life of 100-150k per year, and I’m sure they will argue that a cure should account for the entire life amortization of such a cost. Maybe it will be $5M for someone in their 20s, but only $500k for someone in their 70s.










  • The only solution is to fight it and kill it.

    That’s like saying the only way to get out of being hit by flying debris is to eliminate all wind on the planet. As much as we like to think of Threads as some corporate being, it’s not. It’s a hundred million people that are made of meat and have day jobs like you and me - the wind - and a few million bots and controlled accounts which attempt to influence [whatever their master wishes] - the debris. The debris is already here, and it’s people too - just people with nefarious or profiteering intent. It (debris) happens whenever there are enough people (enough wind) to stir things up.

    Cutting yourself off from people is the only way to prevent it because it’s an inherent function of humanity.


  • He is, unfortunately for his polling, a chief executive that is more involved in production than brand loyalty or celebrity. He’s been in government so long he understands how things get done, what he has the power to move, and what he does not. Tilting at windmills is how you fire up a base but it achieves nothing in practical terms. He’s a tortoise in a world of hares.

    What surprises me is that the pollsters managed to find young voters. Anyone under 35 probably doesn’t answer their phone unless they know the number, and they don’t even have landlines to call from a published list. This was a web-based survey, which sounds rather self-selecting already.